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Drug Repositioning : Bringing New Life to Shelved Assets and Existing Drugs

2012 - John Wiley et Sons Ltd.

498 p.

Indications and Repurpose Existing Drugs,sets forth computational-based strategies, tools, and databases that have been designed for repositioning studies, screening approaches, including combinations of existing drugs, and a look at the development of chemically modified analogs of approved agents. Part 3, Academic and Non-Profit Initiatives & the Role of Alliances in the Drug Repositioning Industry , explores current investigations for repositioning drugs to treat rare and neglected diseases, which are frequently overlooked by for-profit pharmaceutical companies due to their lack of commercial return. The book's appendix provides valuable resources for drug repositioning researchers, including information on drug repositioning and reformulation companies, databases, government resources and organizations, regulatory agencies, and drug repositioning initiatives from academia and non-profits. With this book as their guide, students and pharmaceutical researchers can learn how to use drug repositioning

techniques to extend the lifespan and applications of existing drugs as well as maximize the return on investment in drug research and development. [Publisher's Text]

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