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Testing drugs in Giorgio Baglivi's dissertation on Vesicants

2021 - L'Erma di Bretschneider

P. 271-288

  • Discussions on the medical use of vesicants—a remedy able to induce redness and blisters upon application to the skin—attracted the attention of early-modern physicians due to the severe side effects on the body. Helmontian physicians in particular claim that vesicants are always harmful and, therefore, must be prohibited. Giorgio Baglivi (1668-1707), however, believes that vesicants could be useful under certain conditions. His De usu et abusu vesicantium [On the use and misuse of vesicants] aims at analysing exactly the cases in which such an application is permitted, and the cases in which it is not, and to explain how this remedy works.
  • For Baglivi experimentation on living animals by means of infusory surgery plays a pivotal role in testing the efficacy of drugs or trying and discovering new ones. In this paper, I will provide a short overview of this undeservedly neglected dissertation, by describing Baglivi's experiments on vesicants and their implications for his medical perspective. [Publisher's text]

Is part of

Scientiae in the history of medicine. - ( Storia della medicina ; 4)